Outpatient Infusion Resources

REZZAYO® can be administered in multiple outpatient settings of care

Dosing Image

Dosing & Administration 

Preparation, storage, dosing, and administration.

Efficacy Image

Efficacy and Safety 

Summary of clinical trial data and safety profile.

Efficacy Image

Patient Profiles 

Typical invasive candidiasis patients who may benefit from REZZAYO.

Ordering Image

Ordering 

Specialty distributors, order numbers.

Billing Image

Billing & Coding 

Billing, coding, and NTAP.

Patient Support

Patient Support 

Support, savings, resources, and patient brochure.

Dosing Image

Dosing & Administration 

Preparation, storage, dosing, and administration.

Efficacy Image

Efficacy and Safety 

Summary of clinical trial data and safety profile.

Efficacy Image

Patient Profiles 

Typical invasive candidiasis patients who may benefit from REZZAYO.

Ordering Image

Ordering 

Specialty distributors, order numbers.

Billing Image

Billing & Coding 

Billing, coding, and NTAP.

Patient Support

Patient Support 

Support, savings, resources, and patient brochure.

Dosing Image

Dosing & Administration 

Preparation, storage, dosing, and administration.

Efficacy Image

Efficacy and Safety 

Summary of clinical trial data and safety profile.

Efficacy Image

Patient Profiles 

Typical invasive candidiasis patients who may benefit from REZZAYO.

Ordering Image

Ordering 

Specialty distributors, order numbers.

Billing Image

Billing & Coding 

Billing, coding, and NTAP.

Patient Support

Patient Support 

Support, savings, resources, and patient brochure.

Once-weekly
REZZAYO
®
Week 1

Day 1: 400-mg loading dose

Week 2

Day 8: 200-mg weekly dose

No PICC
required*

VS

Daily IV
echinocandin

Day 1

Day 2

Day 3

Day 4

Day 5

Day 6

Day 7

Day 1

Day 2

Day 3

Day 4

Day 5

Day 6

Day 7

Daily PICC
maintenance
to prevent
infection

*Peripherally inserted central catheter

 

 Global Candidiasis Guideline*
Download Highlights

*Global guideline for the diagnosis and management of candidiasis: an initiative of the ECMM in cooperation with ISHAM and ASM

High early plasma concentrations

See PK Data

INDICATION AND USAGE

REZZAYO® (rezafungin for injection) is an echinocandin antifungal indicated in patients 18 years of age or older who have limited or no alternative options for the treatment of candidemia and invasive candidiasis. Approval of this indication is based on limited clinical safety and efficacy data.

Limitations of Use

REZZAYO® has not been studied in patients with endocarditis, osteomyelitis, and meningitis due to Candida.

IMPORTANT SAFETY INFORMATION

Contraindications

REZZAYO® is contraindicated in patients with known hypersensitivity to rezafungin or other echinocandins.

Warnings and Precautions

  • Infusion-related Reactions: REZZAYO® may cause infusion-related reactions, including flushing, sensation of warmth, urticaria, nausea, or chest tightness. If these reactions occur, slow or pause the infusion.
  • Photosensitivity: REZZAYO® may cause photosensitivity. Advise patients to use protection from sun exposure and other sources of UV radiation.
  • Hepatic Adverse Reactions: Abnormalities in liver tests have been seen in clinical trial patients treated with REZZAYO®. Monitor patients who develop abnormal liver tests and evaluate patients for their risk/benefit of continuing REZZAYO® therapy.

Adverse Reactions

Most common adverse reactions (incidence ≥ 5%) are hypokalemia, pyrexia, diarrhea, anemia, vomiting, nausea, hypomagnesemia, abdominal pain, constipation, and hypophosphatemia.

Please see full Prescribing Information for REZZAYO® (rezafungin for injection).

Important Safety Information  

INDICATION AND USAGE

REZZAYO® (rezafungin for injection) is an echinocandin antifungal indicated in patients 18 years of age or older who have limited or no alternative options for the

 

Contraindications

REZZAYO® is contraindicated in patients with known hypersensitivity to rezafungin or other echinocandins.